Design and Estimation of Fast Dissolving Tablet by using Novel Techniques for Effective Treatment of Diabetes
Dillip Kumar Brahma1, Neeraj sharma2
1Dillip Kumar Brahma, Research Scholar, Dept. of Pharmacy, Sri SatyaSai University of Technology & Medical Sciences, Sehore, Bhopal-Indore Road, Madhya Pradesh, India
2Dr. Neeraj Sharma, Research Guide, Dept. of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Sehore, Bhopal Indore Road, Madhya Pradesh, India
Manuscript received on January 26, 2020. | Revised Manuscript received on February 05, 2020. | Manuscript published on February 30, 2020. | PP: 2345-2349 | Volume-9 Issue-3, February 2020. | Retrieval Number: B3636129219/2020©BEIESP | DOI: 10.35940/ijeat.B3636.029320
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Diabetes mellitus is a metabolic issue it is brought about by a flat out or relative absence of insulin that, among different outcomes, increments in plasma glucose fixation related to change hyperglycemia and unsettling influence of lipid digestion, starch digestion, additionally protein digestion. Glipizide, a secondgen sulfonylurea, is utilized with diet to bring down blood glucose in patients with diabetes mellitus type II. The essential method of activity of glipizide in exploratory creatures seems, by all accounts, to be the incitement of insulin emission from the beta cells of pancreatic islet tissue and is in this way reliant on working -cells in the pancreatic islets. In human’s glipizide seems to bring down the blood glucose intensely by invigorating the arrival of insulin from the pancreas, an impact subordinate after working -cells in the pancreatic islets. In man, incitement of insulin discharge by glipizide because of a feast is undoubtedly vital. Fasting insulin levels are not raised even on long haul glipizide organization, yet the postprandial insulin reaction keeps on being upgraded after at any rate a half year of treatment.
Keywords: Diabetes mellitus, Glipizide, IDDM