Cell Encapsulation Technology-Applications in Therapy
Divya Sanganabhatla
Divya Sanganabhatla, Research Scholar, University College of Technology, Osmania University, Hyderabad (Telangana), India.
Manuscript received on 10 October 2017 | Revised Manuscript received on 18 October 2017 | Manuscript Published on 30 October 2017 | PP: 41-47 | Volume-7 Issue-1, October 2017 | Retrieval Number: A5175107117/17©BEIESP
Open Access | Editorial and Publishing Policies | Cite | Mendeley | Indexing and Abstracting
© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Entrapment of mammalian cells in physical membranes has been practiced since the early 1950s when it was originally introduced as a basic research tool. The method has since been developed based on the promise of its therapeutic usefulness in tissue transplantation. Encapsulation physically isolates a cell mass from an outside environment and aims to maintain normal cellular physiology within a desired permeability barrier. Numerous encapsulation techniques have been developed over the years. These techniques are generally classified as microencapsulation (involving small spherical vehicles and conformally coated tissues) and macroencapsulation (involving larger flat-sheet and hollow-fiber membranes). This review is intended to summarizes the state-of-the-art successes of microencapsulation, specifically with regard to the encapsulation of microorganisms, mammalian cells in treatment of various diseases.
Keywords: Microencapsulated Cell, Probiotic Bacteria, Alginate Solution, Liver Cell.
Scope of the Article: Innovative Mobile Applications