Signature Patterns for Major Virulent Proteins of HIV1
Shashank Mittal1, Reshu Nautiyal2, Swati Mamgain3, Kumud Pant4, Tribhuvan Chandra5
1Shashank Mittal, Department of Biotechnology, Graphic Era University, Dehradun, India.
2Reshu Nautiyal, Department of Biotechnology, Graphic Era University, Dehradun, India.
3Swati Mamgain, Department of Biotechnology, Graphic Era University, Dehradun, India.
4Kumud Pant, Department of Biotechnology, Graphic Era University, Dehradun, India.
5Tribhuvan Chandra, Department of Biotechnology, Graphic Era University, Dehradun, India.
Manuscript received on January 24, 2013. | Revised Manuscript received on February 09, 2013. | Manuscript published on February 28, 2013. | PP: 78-80 | Volume-2 Issue-3, February 2013. | Retrieval Number: C1013022313 /2013©BEIESP
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Realizing the importance of understanding major virulent proteins of HIV we are attempting to unravel various amino acid signatures that exist for two major proteins in HIV i.e. Gag and Env. The results have been obtained through freely available software VESPA available at HIV database project funded by the Division of AIDS of the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH). The results obtained help us to understand the sites in proteins which can be hot spot of mutations or sites where propensity of finding different amino acid exists. This is a novel work where signature patterns for various HIV proteins have been deduced.
Keywords: HIV, AIDS, (NIAID), (NIH).